Center Progress Year 2

Larry A. Sklar. NM Molecular Libraries Screening Center: Enhancing Drug Discovery with Cheminformatics. Society for Biomolecular Screening News 22: 1, 2006.

Chinnasamy Ramesh, Bj Bryant, Tapan Nayak, Chetana M. Revankar, Tamara Anderson, Kathryn E. Carlson, John A. Katzenellenbogen, Larry A. Sklar, Jeffrey P. Norenberg, Eric R. Prossnitz, and Jeffrey B. Arterburn. Linkage
Effects on Binding Affinity and Activation of GPR30 and Estrogen Receptors ERα/β with Tridentate Pyridin-2-yl
Hydrazine Tricarbonyl-Re/99mTc(I) Chelates. J. Am. Chem. Soc. 128: 14476-14477,

Bruce S. Edwards, Susan M. Young, Tudor I. Oprea, Cristian G. Bologa, Eric R. Prossnitz and Larry A. Sklar. Biomolecular Screening of Formylpeptide Receptor Ligands with a Sensitive, Quantitative, High-Throughput Flow Cytometry Platform. Nature Protocols 1(1): 59-66, 2006.

Eric R. Prossnitz, Jeffrey B. Arterburn, Bruce S. Edwards, Larry A. Sklar, Tudor I. Oprea. Steroid-Binding G-Protein-Coupled-Receptors: New Drug Discovery Targets for Old Ligands. Expert Opin. Drug Discov. 1: 137-150, 2006.

Eric R. Prossnitz, Jeffrey B. Arterburn, Larry A. Sklar. GPR30: A G Protein-Coupled Receptor for Estrogen. Mol. Cell. Endocrinol. 265: 138-142, 2007.

Dan C. Fara, Tudor I. Oprea, Eric R. Prossnitz, Cristian G. Bologa, Bruce S. Edwards and Larry A. Sklar. Integration of
virtual and physical screening. Drug Discovery Today: Technologies 2 (4): 377-385, 2006.

Tudor I. Oprea and Alexander Tropsha. Cheminformatics and drug discovery . Drug Discovery Today: Technologies 3 (4): 355-356, 2006.

Tudor I. Oprea and Alexander Tropsha. Target, chemical and bioactivity databases – integration is key. Drug Discovery Today: Technologies 3 (4): 357-365; 2006.

Tudor I. Oprea, Tharun Kumar Allu, Dan C. Fara, Ramon F. Rad, Lili Ostopovici, and Cristian Bologa. Lead-like, drug-like or “Pub-like”: how different are they? J. Comp.-Aided Mol. Design 21(1-3): 113-119; 2007.

Yang Wu, Samuel K. Campos, Gabriel P. Lopez, Michelle A. Ozbun, Larry A. Sklar, and Tione Buranda. The Development of Quantum Dot Calibration Beads and Quantitative Multicolor Bioassays in Flow Cytometry and Microscopy. Anal. Biochem. 364: 180-192, 2007.

Yang Wu, Gabriel P. Lopez, Larry A. Sklar, and Tione Buranda. Spectroscopic Characterization of Streptavidin Functionalized Quantum Dots. Anal. Biochem. 364: 193-203, 2007.

Eugen Brailoiu, Siok L. Dun, G. Cristina Brailoiu, Keisuke Mizuo, Larry A. Sklar, Tudor I. Oprea, Eric R. Prossnitz and Nae J. Dun. Distribution and characterization of estrogen receptor G protein-coupled receptor in the rat central nervous system. J. Endocrin. 193: 311-321, 2007.

Bruce S. Edwards, Susan M. Young, Matthew J. Saunders, Cristian G. Bologa, Tudor I. Oprea, Richard D. Ye, Eric R. Prossnitz, Steven W. Graves, and Larry A. Sklar. High-Throughput Flow Cytometry for Drug Discovery. Expert Opin. Drug Discov. 2(5): 685-696, 2007.

Peter C. Simons, Susan M. Young, Veronica Gibaja, Wen-Cherng Lee, Serene Josiah, Bruce S. Edwards, and Larry A. Sklar. Duplexed, Bead-Based Competitive Assay for Inhibitors of Protein Kinase. Cytometry Part A 71A(7): 451-459, 2007.

University of New Mexico flow cytometry research center